BASi LM Linear Microdialysis Probes

The linear probe consists of a short length of hollow dialysis fiber attached to narrow-bore inlet and outlet tubes. An aqueous perfusion solution, which closely matches the ionic composition of the surrounding extracellular fluid, is pumped through the probe at a constant flow rate. Low molecular weight analytes diffuse in or out of the probe lumen. Large molecules such as proteins or protien-bound analytes are excluded by the membrane. Molecules entering the lumen are swept away by the perfusion fluid. This dialysate is then collected for analysis.

BASi linear microdialysis probes offer a small profile (320 µm OD) and are available with either 10 mm or 5 mm active lengths of dialysis membrane. Custom probes with other membrane lengths are also available. Flexible plastic tubing brackets the membrane window. Long inlet and outlet tubes facilitate subcutaneous externalization of the probes when used in awake animals. An internal fiber strengthens the probe and extends beyond the probe tubing to aid implantation. A plug seals the end of the probe from which the fiber skeleton extends. This plug keeps body fluids from entering the probe during surgery and is cut off before the probe is connected to a syringe pump and perfused. The linear probe is suitable for in vivo sampling from a variety of peripheral tissues, including dermis, subcutaneous tissue, muscle, adipose tissue, liver and other organs.

 

Ordering Information

 

MD-2000	LM-10 Linear Microdialysis Probes, 10 mm membrane window, 6/pkg.
MD-2001	Spare Plastic Tubing for Probe End.
MD-2005	LM-5 Linear Microdialysis Probes, 5 mm membrane window, 6/pkg.
CUSTOM	Any other membrane length, allow 4 weeks for delivery. Please inquire
MR-5314	Veterinary Bonding Glue, 3 mL.
MR-5313	Introducer Needle.
MF-5164	FEP Teflon Tubing, 0.65 mm OD x 0.12 mm ID, 1 meter (clear).
MD-1510	Flanged Tubing Connectors (clear), 20/pkg.
MF-5365	Surgical Instruments Kit.
TM-1000	Tissue Matrix: 10 mm x 10 mm chamber for sectioning dissected tissue into slices for postmortem histology. Other sizes and shapes (V-block, spheres) available.

 

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