BASi
Bioanalytical System Inc.
BASi is a drug development firm providing contract research services and unique products for the pharmaceutical, biotechnology and medical device industries.
LC-4C Amperometric Detector
![[Picture of LC-4C]](images/LC-4C.jpg)
The LC-4C is an analog detector specifically designed for LC/EC, with high current sensitivity, extensive filtering, offset and autozero. In addition to front panel controls, it can also be controlled from a PC using the ChromGraph software. One advantage of PC control is that it allows potential wave forms other than fixed potential to be applied to the cell (e.g., a triple pulse wave form for PAD applications).
There are 2 channels available on the LC-4C - the detector channel, which applies a potential and measures the current response, and the generator channel, which can apply a potential. The detector channel is used in all experiments, whereas the generator channel is only used in experiments in which analyte is electrolyzed before reaching the detector electrode; for example, dual series electrode applications. If the current on both channels needs to be recorded, two LC-4C detectors can be combined, or an LC-4C can used in combination with a Petite Ampere. Alternatively, up to 4 channels can be monitored using the LC epsilon detector.
Features
- Amperometric detector for thin-layer flow cells
- Two channels - generator and detector
- Generator - conducts redox reactions at upstream electrode
- Detector - high current sensitivity, filtering, offset, and autozero
- Controlled from front panel or PC
- PC allows programmable potential wave forms (e.g., for PAD)
- Multi-channel capability with additional LC-4C or Petite Ampere
- Modified LC-4C available for capillary electrophoresis
Specifications
| Channels | Generator and detector channels included. |
| Applied Potential | Generator Channel: 0 ± 1.900 V Detector Channel: 0 ± 1.999 V |
| Gain | Generator Channel: 100 nA/V, 1.0 µA/V, 10 µA/V Detector Channel: 0.1, 0.2, 0.5, 1.0, 2.0, 5.0, 10, 20, 50, 100, 200, 500 nA/V and 1, 2, 5, 10, 20, 50 µA/V. |
| Filter | Generator channel: One-pole filter, non-adjustable for each gain range Detector Channel: Four-pole active filter with 14 settings (0.02, 0.03, 0.04, 0.05, 0.06, 0.08, 0.1, 0.15, 0.2, 0.3, 0.4, 0.5, 0.8, 1.0 Hz) |
| Manual Offset | Detector Channel: 0-10, 0-100, 0-1000 nA |
| Autozero | Detector Channel: Minimum of ± 20 times gain range setting. The rezero point is adjustable to ± 30% of the full-scale setting. Manual and autozero offsets can combine to extend range. |
| Output | Generator Channel: Iout: 1 V (10 V Max.) on terminal strip. Detector Channel: Iout: 1 V full scale (10 V Max.) and 10 mV full scale (100 mV Max.) are available on both banana jacks and the rear panel terminal strip. Eout: Available on terminal strip. |
| Inputs | 2 inputs on rear panel terminal strip for control of autozero and chart marker. Use with TTL low-level and switch closure
outputs on autosamplers and integrators. |
| Control | Connects to PC or ChromGraph DA-5 interface. Controls gain and filter on detector channel, cell on/off, autozero, and chart
marker. Controls potential with ChromGraph software. |
| Power | 100, 120, 220 or 240 VAC, 50/60 Hz, 120 Watts Max. Load |
Amperometric Detectors 