Bioanalytical Chemistry

Bioanalytical chemistry has been a way of life at BASi from the Company’s very beginning in 1974. BASi offers detection, identification and quantification of drug compounds in biological matrices such as blood, plasma, urine, dialysate and tissues using LC/MSMS in support of preclinical drug safety and metabolism research through Phase IV studies. BASi has three bioanalytical laboratories with the capacity to analyze thousands of samples every day. The breadth and quantity of technology and scientific talent give clients high quality data and fast turn-around.

 

Services Overview

• Methods development and validation
• Study sample analysis
• LC/MSMS (triple quadrupole)
• HPLC
• Immunoassay/biomarkers

Capabilities

• High sample throughput
• 37 LC/MSMS instruments
• Sciex API 3000, 4000
• Micromass Quattro LC and Ultima
• Automated 96-well sample preparation available at all sites
• Tomtec Quadra 96 model 320
• Conventional HPLC (UV-Visible, fluorescence, and electrochemical detection)
• Automated microplate robotics
• Grifols Triturus fully automated immunoassays
• Mesoscale Discovery Sector 2400 system
• Molecular Devices SpectraMax M5 reader
• Analysis of unconventional biological tissues
• Low temperature storage
• -80° and -20° C freezer capacity

The BASi Edge

• Method development and validation is a company specialty.
• BASi-developed or client-supplied methods.
• Scientist-to-scientist communication on every project.
• Flexible final report format to meet client preferences.
• Outstanding regulatory history.

Part 11-Compliant Software Systems

• Watson LIMS®
• PE Sciex Analyst®
• Totalchrom®
• Waters Millenium® and Empower®
• MasterControl® Document Management System
• Projects Database System (BASi proprietary, Oracle-based)

Copyright © 2008 Bioanalytical Systems, Inc. All Rights Reserved